A new SPECT reconstruction algorithm based on the Novikov explicit inversion formula

We present a new reconstruction algorithm for single-photon emission computed tomography. The algorithm is based on the Novikov explicit inversion formula for the attenuated Radon transform with non-uniform attenuation. Our reconstruction technique can be viewed as a generalization of both the filtered backprojection algorithm and the Tretiak–Metz algorithm. We test the performance of the present algorithm in a variety of numerical experiments. Our numerical examples show that the algorithm is capable of accurate image reconstruction even in the case of strongly non-uniform attenuation coefficient, similar to that occurring in a human thorax.